00821nam a2200109Ia 4500080001800000100002600018245006000044260005600104300001700160520051500177583001900692  a15.05.01 C654  aGrabrowski, John, ed.  aCocaine : pharmacology, effects, and treatment of abuse  bNational institute on Drug AbuseaRockvilleUSc1984  aviii, 135 p.  aSeries of papers provide a current review of the present knowledge of cocaine.  Discusses the resurgence of cocaine use in the last decade.  Reviews cocaine's neurochemical mechanisms of action.  Identifies specific pharmacological effects relating to absorption, distribution of the drug in the body, metabolism and excretion.  Other aspects include tolerance and dependence. Analyses behavioral effects of cocaine in animals and humans. Discusses changing patterns of use and experimental treatment of abuse.  c3/7/00kM2LMGR