00903nam a2200145Ia 450000500170000008000180001710000260003524500600006126000560012130000170017752005150019458300190070994200120072899900170074020260716042959.0  a15.05.01 C654  aGrabrowski, John, ed.  aCocaine : pharmacology, effects, and treatment of abuse  bNational institute on Drug AbuseaRockvilleUSc1984  aviii, 135 p.  aSeries of papers provide a current review of the present knowledge of cocaine.  Discusses the resurgence of cocaine use in the last decade.  Reviews cocaine's neurochemical mechanisms of action.  Identifies specific pharmacological effects relating to absorption, distribution of the drug in the body, metabolism and excretion.  Other aspects include tolerance and dependence. Analyses behavioral effects of cocaine in animals and humans. Discusses changing patterns of use and experimental treatment of abuse.  c3/7/00kM2LMGR  cMmC654  c38156d38156